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MR-proANP*

Can be of additive diagnostic value to B-type natriuretic peptides

ANP is predominantly produced in the atrium of the heart and comprises 98% of the natriuretic peptides in the circulation. ANP is involved in natriuresis, diuresis, vasodilation and cardiovascular homeostasis. Mature ANP is derived from carboxyl terminal amino acids 99-126 of the prohormone (proANP), which is 126 amino acids in length. The mid-regional portion of the proANP is termed as MR-proANP.

Studies with MR-proANP have shown it may have utility in cardiovascular diseases including congestive heart failure. B·R·A·H·M·S recently presented late-breaking clinical trial information about the results of MR-proANP in the BACH trial at the 2008 European Society of Cardiology.
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For more information on MR-proANP, please call us or send a request to clinical.services@brahms-usa.com.

*MR-proANP is currently available in the US as Research Use Only.