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MR-proADM*

Can predict mortality in cardiac heart failure

Adrenomedullin (ADM) is a multifunctional peptide synthesized by a variety of tissues including heart and kidney. It regulates cardiopulmonary function and vascular tone. MR-proADM, the stable midregion fragment of ADM, is more readily measurable than ADM, yet is secreted in equimolar quantities and therefore provides an accurate portrait of ADM release. MR-proADM shows promise as a powerful predictor for future cardiac events in patients with a history of cardiovascular disease.

Published studies using MR-proADM have shown that it may provide utility in diseases such as congestive heart failure, community-acquired pneumonia and sepsis. B·R·A·H·M·S recently posted information in the Late Breaking Clinical Trials section of the 2008 American Heart Association Scientific Sessions regarding MR-proADM’s superiority over BNP and NT-proBNP in patients presenting with shortness of breath.
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For more information on MR-proADM, please call us or send a request to clinical.services@brahms-usa.com.

*MR-proADM is currently available in the US as Research Use Only.